Part of the aura and rich history of Middlesex County and Greater Middlesex Conference Girls Basketball is the great players that have played over the years. Some of them went on to lead their respective schools in scoring. Below is a table that contains each of the all-time leading scorers who have played in the Greater Middlesex Conference.
All Time Leading Scorers in the Greater Middlesex Conference
| School | Player | Points | Year |
| Calvary Christian | Raegan Fogarty | 1,126 | 2023 |
| Cardinal McCarrick* | Kaitylyn Katko | 1,641 | 2002 |
| Carteret | Ivettelis Castro | 1,909 | 2010 |
| Cedar Ridge* | Gerilyn Shea | 1,516 | 1990 |
| Colonia | Taylor Derkack | 2,062 | 2024 |
| Dunellen | Patty North-Wenzel | 1,549 | 1984 |
| East Brunswick | Jess Olszewski | 1,656 | 2000 |
| East Brunswick Magnet | Jen Enos | 2,161 | 2000 |
| Edison | Samira Sargent | 1,515 | 2019 |
| Highland Park | Vanessa Kohler | 1,670 | 2025 |
| J.P. Stevens | Michelle Morale | 1,622 | 1993 |
| John F. Kennedy | Brittany Washington | 1,168 | 2013 |
| Madison Central* | Eileen Wyer | 1,061 | 1984 |
| Metuchen | Cassie Smith | 2,062 | 2014 |
| Middlesex | Jess Devine | 2,135 | 2025 |
| Monroe | Evangelina Francisco | 1,335 | 2025 |
| Mother Seton | Sawyer West |
1,307 | 2007 |
| New Brunswick | Wakdryea Baker |
2,010 | 2007 |
| North Brunswick | Niyell McCargo | 1,679 | 2023 |
| North Plainfield | Mary Beth Tirrell | 1,364 | 2003 |
| Old Bridge | Jasmine Jackson | 1,854 | 2011 |
| Perth Amboy | Amanda Sepulveda | 1,282 | 2005 |
| Perth Amboy Magnet | Rebecca Hagerty | 1,007 | 2017 |
| Piscataway | Danaejah Grant | 2,566 | 2012 |
| Piscataway Magnet | Iona Scott | 1,581 | 1989 |
| Sayreville | Rhonda Rompola | 1,608 | 1978 |
| South Amboy | Lynn Ust | 2,201 | 1987 |
| South Brunswick | Amber Brown | 1,447 | 2017 |
| South Plainfield | Jill Sosnak | 1,801 | 1990 |
| South River | Gabrielle Harris | 1,741 | 2016 |
| Spotswood | Beth Dickinson | 2,100 | 1999 |
| St. Thomas Aquinas | Emma Boslet | 1,948 | 2020 |
| St. Peter’s* | Kristen Somogyi | 3,899 | 1992 |
| Timothy Christian | Desiree Lothian | 1,387 | 1996 |
| Wardlaw-Hartridge | Janissa Delzo | 1,480 | 2012 |
| Woodbridge | Alex Nardoza | 1,335 | 2011 |
| Woodbridge Academy Magnet | Kiara Rodriguez | 1,394 | 2017 |
* – School no longer exists.