One golden era in Middlesex County boys basketball existed from the mid-1960s to the mid-1970s. From the 1964-65 season to the 1975-76 season, the Perth Amboy Panthers were the most dominant boys hoops program in the area. Perth Amboy won at least 20 games in each of those 12 seasons and played in 9 Middlesex County Tournament Championship Games with 8 titles.
Perth Amboy Panthers – 1964-76 – Win-Loss Records
| Season | Wins | Losses | Win % |
| 1964-65 | 24 | 2 | 0.923 |
| 1965-66 | 23 | 1 | 0.958 |
| 1966-67 | 24 | 1 | 0.960 |
| 1967-68 | 25 | 1 | 0.962 |
| 1968-69 | 26 | 2 | 0.929 |
| 1969-70 | 23 | 1 | 0.958 |
| 1970-71 | 21 | 3 | 0.875 |
| 1971-72 | 24 | 4 | 0.857 |
| 1972-73 | 22 | 5 | 0.815 |
| 1973-74 | 21 | 3 | 0.875 |
| 1974-75 | 23 | 4 | 0.852 |
| 1975-76 | 20 | 7 | 0.741 |
| Totals | 276 | 34 | 0.890 |
| Averages | 23 | 3 | 0.885 |
Perth Amboy Panthers – 1964-76 – Team Stats
| Season | Points Scored | Points Allowed | PPG | PAPG | Diff |
| 1964-65 | 2057 | 1443 | 79.1 | 55.5 | 23.6 |
| 1965-66 | 2164 | 1257 | 90.2 | 52.4 | 37.8 |
| 1966-67 | 2036 | 1407 | 81.4 | 56.3 | 25.2 |
| 1967-68 | 2313 | 1731 | 89.0 | 66.6 | 22.4 |
| 1968-69 | 2327 | 1625 | 83.1 | 58.0 | 25.1 |
| 1969-70 | 1940 | 1353 | 80.8 | 56.4 | 24.5 |
| 1970-71 | 2105 | 1667 | 87.7 | 69.5 | 18.3 |
| 1971-72 | 2304 | 1857 | 82.3 | 66.3 | 16.0 |
| 1972-73 | 1972 | 1662 | 73.0 | 61.6 | 11.5 |
| 1973-74 | 1823 | 1321 | 76.0 | 55.0 | 20.9 |
| 1974-75 | 2153 | 1786 | 79.7 | 66.1 | 13.6 |
| 1975-76 | 1832 | 1735 | 67.9 | 64.3 | 3.6 |
| Totals | 25026 | 18844 | 80.7 | 60.8 | 19.9 |
Perth Amboy Panthers – 1964-76 – County and State Tourneys and Top Players
| Season | MCT | States | Leading Scorer | PPG |
| 1964-65 | Won Title | Lost in CJ Group IV Semis | Jay Ziznewski | 20.4 |
| 1965-66 | Won Title | Lost in CJ Group IV Semis | Jay Ziznewski | 18.8 |
| 1966-67 | Won Title | Won CJ Group IV Title | Larry Larsen | 19.9 |
| 1967-68 | Lost in Elite Eight | Won Group IV State Title | Brian Taylor | 33.7 |
| 1968-69 | Lost in Final Four | Lost in Group IV State Final | Brian Taylor | 38.3 |
| 1969-70 | Won Title | Lost in CJ Group IV Semis | Bruce Carey | 18.7 |
| 1970-71 | Lost in Final Four | Lost in CJ Group IV Final | Howard Dillard | 19.8 |
| 1971-72 | Won Title | Lost in CJ Group III Final | Lamont Clark | 17.5 |
| 1972-73 | Won Title | Lost in CJ Group III Semis | Blake Taylor | 22.8 |
| 1973-74 | Won Title | Lost in CJ Group III Final | Blake Taylor | 27.5 |
| 1974-75 | Won Title | Won CJ Group III Title | Blake Taylor | 29.1 |
| 1975-76 | Lost in Final | Lost in CJ Group III Semis | Chad Kinch | 26.7 |
| Totals | 8-1 in MCT Finals | Won 4 Sectional Titles and One State Title |
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