Middletown South 2021-22 Schedule
| Date | Opponent | Time/Score | Location | Media | Sat, 12 Feb |  Edison | Non-Conference L 41-68 | Frank Cangelosi Gym @ Edison HS (Edison, NJ) | Edison HS Athletics | Mon, 28 Feb |  South Brunswick | Central Jersey Group 4 Opening Round L 47-61 | South Brunswick HS Gym (Monmouth Junction, NJ) | South Brunswick Athletics |
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