| Opening Round (2/28) | ||||
| # | Date | Time | Matchup | Location |
| 1 | 28 Feb 2022 | 18:30 | #1 Rumson-Fair Haven (17-3) 82 - 43 #16 Metuchen (11-13) | Rumson-Fair Haven HS Gym |
| 2 | 28 Feb 2022 | 19:00 | #8 Delaware Valley (17-9) 54 - 36 #9 Hillside (13-7) | Delaware Valley HS Gym |
| 3 | 28 Feb 2022 | 19:00 | #5 Governor Livingston (16-4) 47 - 52 #12 New Providence (10-14) | Governor Livingston HS Gym |
| 4 | 28 Feb 2022 | 19:00 | #4 Holmdel (14-10) 67 - 46 #13 Middlesex (12-14) | Holmdel HS Gym |
| 5 | 28 Feb 2022 | 18:00 | #3 South River (19-7) 59 - 49 #14 A.L. Johnson (14-9) | South River HS Gym |
| 6 | 28 Feb 2022 | 17:00 | #6 Raritan (16-7) 66 - 59 #11 Roselle (14-8) | Raritan HS Gym |
| 7 | 28 Feb 2022 | 17:30 | #7 Nottingham (18-7) 67 - 56 #10 Spotswood (16-8) | Nottingham HS Gym |
| 8 | 28 Feb 2022 | 19:00 | #2 Bound Brook (19-4) 65 - 47 #15 Monmouth Regional (11-12) | Bound Brook HS Gym |
| Quarterfinals (3/2) | ||||
| # | Date | Time | Matchup | Location |
| 9 | 2 Mar 2022 | 18:30 | #1 Rumson-Fair Haven 69 - 52 #8 Delaware Valley | Rumson-Fair Haven HS |
| 10 | 2 Mar 2022 | 18:30 | #4 Holmdel 72 - 52 #12 New Providence | Holmdel HS |
| 11 | 2 Mar 2022 | 17:00 | #3 South River 64 - 78 #6 Raritan | South River HS |
| 12 | 2 Mar 2022 | 19:00 | #2 Bound Brook 65 - 61 #7 Nottingham | Bound Brook HS |
| Sectional Semifinals (3/4) | ||||
| # | Date | Time | Matchup | Location |
| 13 | 4 Mar 2022 | 18:30 | #1 Rumson-Fair Haven 75 - 56 #4 Holmdel | Rumson-Fair Haven HS |
| 14 | 4 Mar 2022 | 19:00 | #2 Bound Brook 50 - 49 #6 Raritan | Bound Brook HS |
| Championship (3/7) | ||||
| # | Date | Time | Matchup | Location |
| 15 | 7 Mar 2022 | 18:30 | #1 Rumson-Fair Haven 75 - 44 #2 Bound Brook | Rumson-Fair Haven HS |
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