| Opening Round (2/28) | ||||
| # | Date | Time | Matchup | Location |
| 1 | 28 Feb 2022 | 18:00 | #1 Marlboro (23-2) 86 - 50 #16 Sayreville (11-13) | Marlboro HS Gym |
| 2 | 28 Feb 2022 | 16:00 | #8 Howell (13-10) 69 - 61 #9 Freehold Township (15-10) | Howell HS Gym |
| 3 | 28 Feb 2022 | 18:30 | #5 Hightstown (13-11) 73 - 55 #12 Montgomery (13-11) | Hightstown HS Gym |
| 4 | 28 Feb 2022 | 19:00 | #4 South Brunswick (17-8) 61 - 47 #13 Middletown South (10-14) | South Brunswick HS Gym |
| 5 | 28 Feb 2022 | 18:30 | #3 Jackson Memorial (18-7) 50 - 33 #14 Rancocas Valley (13-13) | Jackson Memorial HS Gym |
| 6 | 28 Feb 2022 | 17:00 | #6 Northern Burlington 56 - 53 #11 East Brunswick | Northern Burlington HS Gym |
| 7 | 28 Feb 2022 | 17:00 | #7 Trenton 70 - 63 #10 Manalapan | Trenton HS Gym |
| 8 | 28 Feb 2022 | 19:00 | #2 Monroe 50 - 49 #15 Old Bridge | Monroe HS Gym |
| Quarterfinals (3/2) | ||||
| # | Date | Time | Matchup | Location |
| 9 | 2 Mar 2022 | 16:00 | #1 Marlboro 77 - 64 #8 Howell | Marlboro HS |
| 10 | 2 Mar 2022 | 17:30 | #4 South Brunswick 68 - 62 #12 Montgomery | South Brunswick HS |
| 11 | 2 Mar 2022 | 19:00 | #3 Jackson Memorial 62 - 49 #6 Northern Burlington | Jackson Memorial HS |
| 12 | 2 Mar 2022 | 19:00 | #2 Monroe 59 - 65 #7 Trenton | Monroe HS |
| Sectional Semifinals (3/4) | ||||
| # | Date | Time | Matchup | Location |
| 13 | 4 Mar 2022 | 16:00 | #1 Marlboro 55 - 46 #4 South Brunswick | Marlboro HS |
| 14 | 4 Mar 2022 | 19:00 | #3 Jackson Memorial 56 - 57 #7 Trenton | Jackson Memorial HS |
| Championship (3/7) | ||||
| # | Date | Time | Matchup | Location |
| 15 | 7 Mar 2022 | TBA | #1 Marlboro 75 - 67 #3 Jackson Memorial | Marlboro HS |
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