| First Round (2/9) | ||||
| # | Date | Time | Matchup | Location |
| 1 | 9 Feb 2022 | 16:00 | #1 St. Joseph - #16 J.F. Kennedy | St. Joseph |
| 2 | 9 Feb 2022 | 16:00 | #8 South Brunswick - #9 South Plainfield | South Brunswick HS |
| 3 | 9 Feb 2022 | 16:00 | #5 Colonia - #12 Sayreville | Colonia HS |
| 4 | 9 Feb 2022 | 16:00 | #4 Perth Amboy - #13 North Brunswick | Perth Amboy HS |
| 5 | 9 Feb 2022 | 16:00 | #3 St. Thomas Aquinas - #14 Old Bridge | St. Thomas Aquinas HS |
| 6 | 9 Feb 2022 | 16:00 | #6 Woodbridge - #11 Piscataway | Woodbridge HS |
| 7 | 9 Feb 2022 | 16:00 | #7 East Brunswick - #10 Edison | East Brunswick HS |
| 8 | 9 Feb 2022 | 16:00 | #2 Monroe - #15 J.P. Stevens | Monroe HS |
| Quarterfinals (2/11) | ||||
| # | Date | Time | Matchup | Location |
| 9 | 11 Feb 2022 | 16:30 | #1 St. Joseph - #8 South Brunswick | St. Joseph HS |
| 10 | 11 Feb 2022 | 16:00 | #4 Perth Amboy - #5 Colonia | Perth Amboy HS |
| 11 | 11 Feb 2022 | 16:00 | #3 St. Thomas Aquinas - #6 Woodbridge | St. Thomas Aquinas HS |
| 12 | 11 Feb 2022 | 16:00 | #2 Monroe - #7 East Brunswick | Monroe HS |
| Semifinals (2/15) | ||||
| # | Date | Time | Matchup | Location |
| 13 | 15 Feb 2022 | 15:45 | #2 Monroe 57 - 59 #3 St. Thomas Aquinas | Perth Amboy HS |
| 14 | 15 Feb 2022 | 17:15 | #1 St. Joseph - #5 Colonia | Perth Amboy HS |
| Championship (2/17) | ||||
| # | Date | Time | Matchup | Location |
| 15 | 17 Feb 2022 | 16:00 | #1 St. Joseph 65 - 67 #3 St. Thomas Aquinas | Perth Amboy HS |
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